Hydroxypinacolone Retinoate(HPR)-CAS 893412-73-2
Product Name: Hydroxypinacolone Retinoate
Abbreviation: HPR
INCI Name: Hydroxypinacolone Retinoate
CAS No.: 893412-73-2
Grade: Cosmetic Premium Grade (Third-generation Mild High-efficiency Retinoid Special)
Purity: ≥99.0%
Appearance: Fine Yellow Crystalline Powder, Uniform Fineness, No Caking, Odorless, Pure Texture
Molecular Formula: C₂₀H₂₈O₃
Molecular Weight: 316.44
MOQ (Minimum Order Quantity): 25KG
Solubility: Excellent lipophilic solubility, soluble in most cosmetic oil-phase systems; compatible with emulsions and water-oil composite formulas; stable performance, no precipitation, no stratification, easy formula integration
Core Efficacy: Mild anti-aging and anti-wrinkle, promote skin keratin renewal, unclog pores, remove acne and closed comedones, fade fine lines, smooth skin texture, improve rough dull skin, repair damaged skin
Key Characteristics: New third-generation retinoid active ingredient, alternative to traditional retinol and retinoic acid; high-efficiency anti-aging with ultra-low irritation, non-photosensitive, no skin peeling and redness, available for daytime use, stable formula activity, suitable for sensitive skin anti-aging care
Storage Condition: Sealed and stored in dry, cool and ventilated warehouse, avoid high temperature, humidity and strong light exposure; keep tightly sealed after opening to prevent moisture absorption and activity attenuation
Shelf Life: 24 Months
Application: Widely used in anti-aging essence, anti-wrinkle cream, acne repair lotion, exfoliating skincare, delicate skin maintenance and mild retinoid functional cosmetic formulas
Hydroxypinacolone Retinoate, HPR, Cosmetic Grade HPR, Mild Retinoid, Anti-aging, Anti-wrinkle, Acne Removal, Exfoliating, Non-photosensitive Skincare Raw Material
Hydroxypinacolone Retinoate(HPR)-CAS 893412-73-2
Cosmetic Grade Hydroxypinacolone Retinoate (HPR) is a new third-generation innovative retinoid derivative, professionally optimized to solve the pain points of traditional retinol ingredients such as strong irritation, photosensitivity, easy inactivation and skin peeling. Different from first and second-generation retinoids, HPR has a unique molecular structure, which can directly bind to skin retinoic acid receptors without intermediate conversion, featuring high-efficiency and rapid skin efficacy.
It can effectively promote the renewal and metabolism of skin keratinocytes, accelerate the shedding of aged waste keratin, unclog blocked pores, inhibit acne bacteria breeding, and significantly improve acne, closed comedones and rough skin problems. In terms of anti-aging performance, HPR stimulates collagen synthesis, enhances skin elasticity and compactness, fades dynamic and static fine lines, delays skin sagging and aging, and smooths uneven skin texture.
Most importantly, HPR abandons the irritation defects of traditional retinoids, with ultra-mild skin-friendly properties, no photosensitivity, no redness or peeling after long-term use, and can be safely used for daytime continuous anti-aging care. It has excellent formula stability, wide compatibility with mainstream skincare actives, does not affect finished product color and fragrance, and is a high-quality mild anti-aging core raw material for sensitive skin and beginner anti-aging skincare.
Key Benefits
• Third-generation Mild Retinoid, Zero Irritation Anti-aging: Upgraded new retinoid ingredient, compared with traditional retinol and retinoic acid, it has no irritation, no peeling, no redness, solves the problem of retinoid intolerance, and realizes gentle anti-aging.
• Non-photosensitive & All-day Available: No photosensitive risk, breaks the limitation that traditional retinol can only be used at night, supports daytime long-term anti-aging care, prevents light aging, and improves anti-aging efficiency comprehensively.
• Direct Receptor Binding, High-efficiency Efficacy: No intermediate conversion required, directly acts on skin retinoic acid receptors, efficiently promotes keratin renewal and collagen regeneration, with faster and more thorough anti-wrinkle and skin smoothing effect.
• Acne Removal & Pore Refining, Dual Skin Regulation: Unclog pores, inhibit acne growth, improve closed comedones and inflammatory acne, refine enlarged pores, balance skin oil secretion, and maintain stable skin state.
• Excellent Formula Stability, Not Easy to Inactivate: Stable chemical properties, not easy to oxidize and inactivate, wide pH adaptation range, compatible with various oil-water systems, convenient for formula debugging and industrial mass production.
• Sensitive Skin Adaptable, Wide Audience Coverage: Ultra-mild molecular structure, low skin burden, suitable for sensitive skin, fragile skin and retinoid beginner skin, realizing universal safe anti-aging maintenance.
Applications
• Mild Anti-aging & Anti-wrinkle Essence: Core active ingredient of beginner anti-aging essence and sensitive skin anti-wrinkle serum, gently fade fine lines, activate collagen vitality, and delay initial skin aging.
• Acne & Closed Comedones Repair Lotion: Added in oil-control acne lotion and pore-refining skincare products, unclog pores, inhibit acne recurrence, improve rough and greasy skin texture.
• Daytime All-weather Anti-aging Cream: Suitable for daytime anti-aging cream and firming skincare formulas, relying on non-photosensitive characteristics to resist light aging and maintain long-term young skin state.
• Keratin Renewal & Exfoliating Skincare: Applied in gentle exfoliating products and skin smoothing maintenance products, accelerate aged keratin shedding, improve dull and rough skin, and restore delicate skin texture.
• Sensitive Skin Anti-initial Aging Series: Build high-safety mild anti-aging formulas for sensitive skin, avoid irritation and barrier damage, and solve initial aging problems such as fine lines and sagging gently.
• High-end Compound Anti-aging System: Compounded with peptides, hyaluronic acid and antioxidant ingredients to build multi-dimensional anti-aging skincare system, improve product efficacy barriers and market competitiveness.
Certificate Of Analysis (COA)
Test Item | Standard Specification | Test Result |
Product Name | Hydroxypinacolone Retinoate (HPR) | Compliant |
CAS No. | 893412-73-2 | Compliant |
Appearance | Fine Yellow Crystalline Powder | Compliant |
Purity (HPLC) | ≥99.0% | 99.56% |
Loss on Drying | ≤0.5% | 0.13% |
Residue on Ignition | ≤0.1% | 0.04% |
Heavy Metal (Pb) | ≤1ppm | 0.2ppm |
Arsenic (As) | ≤0.5ppm | 0.1ppm |
Total Bacteria | ≤100CFU/g | Qualified |
Pathogenic Bacteria | Negative | Negative |
Conclusion | Conforms to cosmetic grade quality standard | Qualified |
Frequently Asked Questions (FAQ)
• Q1: What is the MOQ of HPR?
A1: The standard MOQ is 25KG, and sample orders are supported for formula testing and anti-aging efficacy trial production.
• Q2: What certification documents can be provided?
A2: Complete COA, MSDS, heavy metal and microbial test reports and full set of customs clearance documents are available to support export declaration and cosmetic product filing.
• Q3: What is the recommended dosage in cosmetic formulas?
A3: Conventional addition dosage is 0.1%-0.3% for daily anti-aging lotion and cream; 0.3%-0.6% for high-efficiency anti-wrinkle and acne repair essence, adjustable according to anti-aging and skin conditioning requirements.
• Q4: What is the difference between HPR and traditional retinol?
A4: Traditional retinol is photosensitive, irritating and easy to cause peeling and redness, only suitable for night use. HPR is a third-generation retinoid, non-photosensitive, ultra-mild, no skin intolerance, available all day, with more stable efficacy and wider applicability.
• Q5: Is HPR suitable for sensitive skin formulas?
A5: Yes, HPR has ultra-mild properties, no irritation and no sensitization. It solves the intolerance problem of traditional retinoids and is the preferred anti-aging raw material for sensitive skin and fragile skin.
• Q6: Can HPR be compounded with other skincare ingredients?
A6: It has excellent synergistic effect with peptides, ceramides, hyaluronic acid and VC derivatives, forming a multi-dimensional skincare system of anti-aging, repair and brightening to double product efficacy.
• Q7: Do you support stable large-batch supply all year round?
A7: Standardized purification production lines ensure sufficient inventory and stable annual output, supporting long-term cooperative orders and customized formula matching services.
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